The B Vitamins, such as B1, B2, B3, B5, B6, B12 and folate, do a lot within your body to support estrogen detoxification. Conversely, if your body is deficient in B vitamins, you will have higher levels of circulating estrogens. By now, you definitely know that increased estrogen levels lead to estrogen dominance and estrogen dominance will most certainly lead to weight gain and the inability to get that weight off. B vitamins also impact estrogen activity for the hormone receptors at the cellular level. Clinical studies have shown that high levels of intracellular (e.g. within the cell) B6 can decrease the binding response at the estrogen hormone receptor site. What happens at the cellular level is sort of like an internal game of musical chairs: If the music stops and B6 sits down in the “estrogen chair” then the estrogen molecule is out of the game. Because the B vitamins work together to perform such vital tasks at the cellular level, I recommend that you take the entire B-complex, not just one or two of the vitamins. To treat symptoms of hormone imbalance, you will need between 50-100 mg of B Complex that contains 50 mgs of thiamine (B1), riboflavin (B2), niaicin (b3), pantothenic acid (b5), P6, PABA, choline, inositol,; 50 mcg B12, and 400 mcg of folic acid. Ingredients: Thiamin (thiamin HCl) 100 mg. Riboflavin (vitamin B-2) 100 mg. Niacinamide 100 mg. Vitamin B-6 (from 122 mg. pyridoxine HCl) 100 mg. Folic Acid 400 mcg. Vitamin B-12 (cobalamin) 100 mcg. Biotin 100 mcg. Pantothenic Acid (from 109 mg. d-calcium pantothenate) 100 mg. Inositol 100 mg. P.A.B.A. 50 mg . Choline (from 100 mg. choline bitartrate) 47 mg . Other ingredients: rice bran, deep mined calcium phosphate, natural silica, vegetable stearates, and 100% natural preservative-free gelatin (capsule shell). NO corn, soy, salt, yeast, wheat, milk & egg products, sugar, starch, or preservatives. One capsule daily, as a dietary supplement.